After weeks of lockdown easing across the planet, there are signs of a second wave of infections in key cities, jolting the investor confidence that has helped power a surge in equities from their March trough.

Bars in Los Angeles and six other counties in California -- with a joint population of more than 13 million people -- were ordered to close up again, just over a week after reopening, while San Francisco is stalling its easing measures.

There has also been a sharp pick-up in Texas and Florida, two of the most populous American states and home to a combined 50 million people.

Other big states including Arizona and Georgia have also seen large jumps in cases.

"This is a very, very serious situation and the window is closing for us to take action and get this under control," said Health and Human Services Secretary Alex Azar.

Stephen Innes at AxiCorp warned that increased mobility as parts of the country returned to business had likely led to the recent rise in coronavirus infections.

That had in turn caused "a reversal of mobility trends and a reduction in economic activity, particularly in the hardest-hit states," he said.

OANDA's Jeffrey Halley added that the trajectory of new infections in the US was still a "primary concern" for investors.

"As the consumer of last resort for the rest of the world for so long, an aggressive double-dip in the US economic recovery will surely see the rest of the world catch a cold," Halley said.

- Worry for Europe -

The issue is not confined to the US.

China has imposed a strict lockdown on nearly half a million people in a province surrounding Beijing to contain a fresh cluster, with a city official calling the situation "severe and complicated".

Asian markets tracked steep losses in New York on Friday.

Tokyo lost more than two percent and Seoul was 1.9 percent off, while Sydney, Mumbai, Taipei, Manila and Singapore lost more than one percent each.

Hong Kong sank 1.3 percent as investors there keep a nervous eye on this week's July 1 China handover anniversary, fearful of fresh protests.

Shanghai finished 0.6 percent lower, with little solace in upbeat weekend data showing profits at Chinese industrial firms rose last month for the first time since November.

There were also losses in Jakarta and Bangkok, while London, Paris and Frankfurt all opened lower.

"Equity market consolidation is broadly in line with our thinking that equities were getting ahead of economic fundamentals," said Tai Hui, a strategist at JP Morgan Asset Management.

"The rebound of the infection rate, especially in the US, shows that the road to full recovery is going to be long," he added.

Concerns about the impact on demand from the reimposition of some containment measures weighed on oil markets, with both main contracts down more than one percent, having lost around three percent last week.

And analysts said the commodity would have suffered heavier losses were it not for massive output cuts by major producers.

- Key figures around 0720 GMT -

Tokyo - Nikkei 225: DOWN 2.3 percent at 21,995.04 (close)

Hong Kong - Hang Seng: DOWN 1.3 percent at 24,241.88

Shanghai - Composite: DOWN 0.6 percent at 2,961.52 (close)

London - FTSE 100: DOWN 0.3 percent at 6,140.00

West Texas Intermediate: DOWN 1.5 percent at $37.77 per barrel

Brent North Sea crude: DOWN 1.9 percent at $40.26 per barrel

Euro/dollar: UP at $1.1260 from $1.1218 at 2100 GMT on Friday

Dollar/yen: DOWN at 107.05 yen from 107.22 yen

Pound/dollar: UP at $1.2378 from $1.2336

Euro/pound: UP at 90.97 pence from 90.92 pence

New York - Dow: DOWN 2.8 percent at 25,015.55 (close)

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